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The kidney donor profile index (KDPI) combines a variety of donor factors into a single number that summarizes the likelihood of graft failure after deceased donor kidney transplant.The KDPI tells you how long a deceased donor kidney is expected to function relative to all of the kidneys recovered in the U.S. during the last year.
KDRI >2.2 is a useful discriminatory cut-off for the determination of graft survival benefit with the use of DKT; however, the benefit of increased graft years was less than half of single kidneys from donors in the same KDRI range. The Kidney Dono r Risk Index (KDRI) is an estimate of the relative risk of post-transplant kidney graft failure (in an average, adult recipient) from a particular deceased donor compared to the median (50. th. The KDPI/KDRI of the second transplant for those patients awaiting a 3KT was not statistically different from those awaiting a first transplant, 48%/0.980 (sd 0.32) vs. 48%/0.979 (sd 0.330), p>0.05). The majority (65%) of deceased donor kidneys have KDPI between 21 and 85% and are expected to function for about 9 years. This decision depends on a variety of factors, including your transplant center’s expected waiting times, the patient’s clinical characteristics, whether living donation is a possibility, and quality of life considerations. The calculations and assumptions mirror those used for computing KDPI and KDRI in DonorNetThis is an official U.S. Government Web site managed by the KDPI is not intended to serve as the only metric for determining donor suitability.Yes. In the same way the ECD list was intended to help transplant more quickly patients that may not require a high-longevity kidney, consenting and listing a patient as willing to accept a KDPI>85% kidney is also expected to expand opportunities for transplantation.Access professional and patient education materials about the new kidney allocation system, including the following.This is an official U.S. Government Web site managed by the Kidney Donor Profile Index (KDPI) Guide for Clinicians The KDRI expresses the relative risk of kidney graft failure for a given donor compared to the median kidney donor from last year; values exceeding 1 have higher expected risk than the median donor, and vice versa.The KDPI is a remapping of the KDRI onto a cumulative percentage scale, such that a donor with a KDPI of 80% has higher expected risk of graft failure than 80% of all kidney donors recovered last year and can be used to compute KDPI and KDRI for a hypothetical or actual donor. percentile) donor. Figure 1 shows that a deceased donor kidney with KDPI of 0-20% is expected to function, on average, nearly 11 and a half years after transplant, compared to over 12 years for a living donor kidney. The KDRI represents the relative risk of post-transplant graft failure from a particular deceased donor compared to the donor in the 50 th percentile of risk, with the recipient characteristics being set to the population average values . Kidneys with KDPI exceeding 85% are expected to function for more than five and a half years.Since living donor kidneys have tended to be transplanted into lower-risk patients (e.g., younger, non- diabetic), and KDPI > 85% kidneys have tended to go to higher-risk patients, the actual differences in half-lives for a given patient may not be as great as shown in Figure 1. The Kidney Donor Risk Index (KDRI) combines a variety of donor factors to summarize the risk of graft failure after kidney transplant into a single number.
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